Carbon-monoxide Encephalopathy

Delayed encephalopathy following carbon monoxide intoxication.

The case history and CT scan of a patient with delayed encephalopathy following carbon monoxide intoxication are described. The patient recovered. The CT scan revealed symmetrical areas of decreased density at the level of the globus pallidus. This case differs in several ways from other cases of carbon monoxide intoxication in which abnormalities of the CT scan were found.

Predictors for delayed encephalopathy following acute carbon monoxide poisoning

BACKGROUND In Japan, many carbon monoxide (CO) poisoning cases are transported to emergency settings, making treatment and prognostic assessment an urgent task. However, there is currently no reliable means to predict whether "delayed neuropsychiatric sequelae (DNS)" will develop after acute CO poisoning. This study is intended to find out risk factors for the development of DNS and to characte...

Delayed post-anoxic encephalopathy without relation to carbon monoxide poisoning.

Delayed post-anoxic encephalopathy (DPE) not related to carbon monoxide has rarely been reported and usually carries a poor prognosis. We describe two surviving patients with such DPE and its neuro-otological characteristics. The DPE was caused by shock due to hemorrhage in a 21-year-old student, and by severe hypoxia and hypotension in a 60-year-old man. Our findings suggest that this type of ...

Delayed encephalopathy after carbon monoxide intoxication: prognosis is still uncertain.

Biological signaling by carbon monoxide and carbon monoxide-releasing molecules.

Carbon monoxide (CO) is continuously produced in mammalian cells during the degradation of heme. It is a stable gaseous molecule that reacts selectively with transition metals in a specific redox state, and these characteristics restrict the interaction of CO with defined biological targets that transduce its signaling activity. Because of the high affinity of CO for ferrous heme, these targets...